Your enquiry0Mitochondrial research
RESEARCH USE ONLYElamipretide, MTP-131
SS-31, also known as elamipretide or MTP-131, is a synthetic tetrapeptide studied for interactions with mitochondrial cardiolipin. Select your format and quantity for pricing, batch availability and lead time.
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ABOUT THE MATERIAL
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SS-31, also known as elamipretide or MTP-131, is a synthetic tetrapeptide studied for interactions with mitochondrial cardiolipin.[Sources]
Its aromatic-cationic structure is examined in inner-membrane models, with attention to the cytochrome c/cardiolipin complex, electron transfer and ATP synthesis.
Cardiolipin interaction, cytochrome c peroxidase activity, oxygen consumption and ATP recovery describe separate steps. The cited work combines membrane-level analysis with mitochondrial function measurements.
A CLOSER LOOK
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A fluorescent analogue and biochemical assays were used to study SS-31–cardiolipin interaction. Rat renal-ischemia experiments examined mitochondrial cristae, swelling and ATP recovery. Together, these measurements connect membrane interaction with mitochondrial and tissue responses.
Liposomes, membrane systems and isolated mitochondria were used to examine SS-31 and the cytochrome c/cardiolipin complex. The experiments distinguished peroxidase activity from electron-carrier function and measured respiration and ATP synthesis.
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BEFORE YOU ENQUIRE
Cardiolipin interaction, cytochrome c peroxidase activity, oxygen consumption and ATP recovery describe separate steps. The cited work combines membrane-level analysis with mitochondrial function measurements.
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The displayed value is a catalogue specification. Assess the offered lot against its matching COA and method. Chromatographic purity, component content and biological activity are different measurements; confirm which results are available.
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SOURCES
Content updated
Birk AV, Liu S, Soong Y, Mills W, Singh P, Warren JD, Seshan SV, Pardee JD, Szeto HH. 2013, DOI: 10.1681/asn.2012121216
Biochemical experiments and rat kidney ischemia model
Birk AV, Chao WM, Bracken C, Warren JD, Szeto HH. 2014, DOI: 10.1111/bph.12468
Liposomes, NMR and mitochondrial assays
Publications describe their own study materials and methods. They are distinct from BatchTide specifications and lot-release records. Materials listed here are for laboratory research only, not for human or veterinary use.
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