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RESEARCH USE ONLYMT-2, MT-II
Melanotan II is a cyclic heptapeptide melanocortin agonist used in receptor, food-intake and energy-expenditure research. Select your format and quantity for pricing, batch availability and lead time.
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ABOUT THE MATERIAL
Identity, scientific context and the details that distinguish this entry.
Melanotan II is a cyclic heptapeptide melanocortin agonist used in receptor, food-intake and energy-expenditure research.[Sources]
Its structure includes an N-terminal acetylated norleucine and a lactam ring between Asp and Lys residues. The cited mouse study uses MC4R deletion to examine receptor contributions to metabolic responses.
Comparing wild-type with MC4R-deficient animals helps identify the receptor contribution to food-intake and metabolic-rate endpoints. Melanotan II is a nonselective ligand, so receptor contribution and ligand selectivity are different questions.
A CLOSER LOOK
Read each finding with its study model and material identity.
Wild-type and MC4R-knockout mice were compared after Melanotan II exposure. Differences in food intake and metabolic rate supported a contribution of MC4R to those acute responses. The study uses a nonselective melanocortin ligand in a receptor-defined experimental design.
PRODUCT DATA
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BATCH DOCUMENTATION
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BEFORE YOU ENQUIRE
Comparing wild-type with MC4R-deficient animals helps identify the receptor contribution to food-intake and metabolic-rate endpoints. Melanotan II is a nonselective ligand, so receptor contribution and ligand selectivity are different questions.
Use the specification and available safety or stability information for the offered lot, form and packaging. Request written conditions before ordering; literature alone does not establish a universal temperature, shelf life or reconstitution procedure.
The displayed value is a catalogue specification. Assess the offered lot against its matching COA and method. Chromatographic purity, component content and biological activity are different measurements; confirm which results are available.
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SOURCES
Content updated
Chen AS, Metzger JM, Trumbauer ME, Guan XM, Yu H, Frazier EG, Marsh DJ, Forrest MJ, Gopal-Truter S, Fisher J, Camacho RE, Strack AM, Mellin TN, MacIntyre DE, Chen HY, Van der Ploeg LH. 2000, DOI: 10.1023/a:1008983615045
Wild-type and MC4R-deficient mice
NCBI PubChem
Cyclic peptide connectivity and chemical identity
Publications describe their own study materials and methods. They are distinct from BatchTide specifications and lot-release records. Materials listed here are for laboratory research only, not for human or veterinary use.
EXPLORE THE CATALOGUE
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