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RESEARCH USE ONLYGRF 1-29 NH2
Sermorelin is the amidated GHRH(1–29) peptide used to study growth hormone-releasing hormone receptor signaling and pituitary GH release. Select your format and quantity for pricing, batch availability and lead time.
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ABOUT THE MATERIAL
Identity, scientific context and the details that distinguish this entry.
Sermorelin is the amidated GHRH(1–29) peptide used to study growth hormone-releasing hormone receptor signaling and pituitary GH release.[Sources]
It represents the active N-terminal region of GHRH. Early sequence and activity experiments established that this short region retains GH-releasing activity in pituitary assays.
Sermorelin belongs to the GHRH-receptor pathway. GHRP-6 and ipamorelin belong to the secretagogue/ghrelin-receptor pathway. Receptor-specific assays distinguish these routes to GH release.
A CLOSER LOOK
Read each finding with its study model and material identity.
Sequence analysis characterized human growth hormone-releasing factor and compared synthetic fragments in pituitary assays. The amidated 1–29 region retained GH-releasing activity under the tested conditions. This establishes an experimental foundation for the active N-terminal GHRH fragment.
PRODUCT DATA
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BEFORE YOU ENQUIRE
Sermorelin belongs to the GHRH-receptor pathway. GHRP-6 and ipamorelin belong to the secretagogue/ghrelin-receptor pathway. Receptor-specific assays distinguish these routes to GH release.
Use the specification and available safety or stability information for the offered lot, form and packaging. Request written conditions before ordering; literature alone does not establish a universal temperature, shelf life or reconstitution procedure.
The displayed value is a catalogue specification. Assess the offered lot against its matching COA and method. Chromatographic purity, component content and biological activity are different measurements; confirm which results are available.
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SOURCES
Content updated
Spiess J, Rivier J, Thorner M, Vale W. 1982, DOI: 10.1021/bi00267a002
Rat pituitary assays of human releasing-factor fragments
Publications describe their own study materials and methods. They are distinct from BatchTide specifications and lot-release records. Materials listed here are for laboratory research only, not for human or veterinary use.
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