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RESEARCH USE ONLYGrowth Hormone Releasing Hexapeptide
GHRP-6 is a synthetic hexapeptide agonist of the growth hormone secretagogue/ghrelin receptor, used in GH-release and receptor-signaling assays. Select your format and quantity for pricing, batch availability and lead time.
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ABOUT THE MATERIAL
Identity, scientific context and the details that distinguish this entry.
GHRP-6 is a synthetic hexapeptide agonist of the growth hormone secretagogue/ghrelin receptor, used in GH-release and receptor-signaling assays.[Sources]
The peptide supports comparison of calcium mobilization, phosphoinositide signaling and transcriptional reporters within the GHS-R system. This receptor pathway is distinct from GHRH-receptor signaling.
Calcium, inositol-phosphate and reporter assays sample different parts of the signaling cascade. Compare the same readout, receptor expression and exposure conditions when ranking ligands.
A CLOSER LOOK
Read each finding with its study model and material identity.
The receptor-characterization study examined rat pituitary and hypothalamic GHS-R. Expression and ligand-response experiments established a signaling system distinct from GHRH receptors, providing a molecular framework for GH-secretagogue peptide comparisons.
Receptor assays compared GHRP-6 with nonpeptide ligands using calcium, phosphoinositide and transcriptional-reporter endpoints. Relative potency varied with the readout. The study demonstrates how assay selection affects comparisons among ligands sharing GHS-R.
PRODUCT DATA
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BATCH DOCUMENTATION
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BEFORE YOU ENQUIRE
Calcium, inositol-phosphate and reporter assays sample different parts of the signaling cascade. Compare the same readout, receptor expression and exposure conditions when ranking ligands.
Use the specification and available safety or stability information for the offered lot, form and packaging. Request written conditions before ordering; literature alone does not establish a universal temperature, shelf life or reconstitution procedure.
The displayed value is a catalogue specification. Assess the offered lot against its matching COA and method. Chromatographic purity, component content and biological activity are different measurements; confirm which results are available.
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SOURCES
Content updated
McKee KK, Palyha OC, Feighner SD, Hreniuk DL, Tan CP, Phillips MS, Smith RG, Van der Ploeg LH, Howard AD. 1997, DOI: 10.1210/mend.11.4.9908
Cloned rat growth-hormone secretagogue receptor
Holst B, Brandt E, Bach A, Heding A, Schwartz TW. 2005, DOI: 10.1210/me.2005-0059
Growth-hormone secretagogue receptor signaling assays
Publications describe their own study materials and methods. They are distinct from BatchTide specifications and lot-release records. Materials listed here are for laboratory research only, not for human or veterinary use.
EXPLORE THE CATALOGUE
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